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In general, e-cigarettes contain a lower dose of nicotine: Ranging from 6 to 30 milligrams of nicotine per milliliter of liquid However, Juul contains a much higher concentration of nicotine: 59 milligrams of nicotine per milliliter of liquid In fact, according to Juul, one Juul pod contains about the same amount of nicotine as one pack of cigarettes